Enhancement of cell-mediated immune response in mice by whole HIV-1 gag in mycobacterium bovis BCG as a live vaccine candidate

In this study, we employed a recombinant Mycobacterium bovis Bacille Calmette-Guerin (BCG) harboring whole HIV-1 CRF01-AE gag DNA as a candidate vaccine to investigate specific cell-mediated immunity in BALB/c mice. Construction of the stable expression recombinant BCG was achieved by demonstrating...

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Bibliographic Details
Main Authors: Duanthanorm Promkhatkaew, Nadthanan Pinyosukhee, Wilai Thongdeejaroen, Reungpung Sutthent, Pathom Sawanpanyalert, Paijit Warachit
Other Authors: Thailand Ministry of Public Health
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/28261
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Institution: Mahidol University