Inhibitory effects of asiatic acid and CPT-11 on growth of HT-29 cells

• المؤلفون الرئيسيون: Bunpo P., Kataoka K., Arimochi H., Nakayama H., Kuwahara T., Vinitketkumnuen U., Ohnishi Y.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-15544366910&partnerID=40&md5=1e12ddb8664df0fed5a5e674cd3c76d3; http://cmuir.cmu.ac.th/handle/6653943832/1962
• المؤسسة: Chiang Mai University

Asiatic acid is a pentacyclic triterpene contained in medicinal plants. The cytotoxic effect of this compound and its augmentative effect on the anticancer drug irinotecan hydrochloride (CPT-11) were investigated in the human colon adenocarcinoma cell line HT-29. Asiatic acid dose-dependently showed...