Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells

• المؤلفون الرئيسيون: Anuchapreeda S., Thanarattanakorn P., Sittipreechacharn S., Tima S., Chanarat P., Limtrakul P.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-33751317436&partnerID=40&md5=8336c13c14abc055e924343de1b2631d; http://www.ncbi.nlm.nih.gov/pubmed/17121181; http://cmuir.cmu.ac.th/handle/6653943832/2023

When patients with cancers are treated with chemotherapeutic agents a long time, some of the cancer cells develop the multidrug resistance (MDR) phenotype. MDR cancer cells are characterized by the overexpression of multidrug resistance1 (MDR1) gene which encodes P-glycoprotein (Pgp), a surface prot...