Chondroitinase-mediated degradation of rare 3-O-sulfated glucuronic acid in functional oversulfated chondroitin sulfate K and E

• Main Authors: Fongmoon D., Shetty A.K., Basappa, Yamada S., Sugiura M., Kongtawelert P., Sugahara K.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-37549032527&partnerID=40&md5=63e679b96476858eecf57c2e0d5c73e4; http://cmuir.cmu.ac.th/handle/6653943832/2081

Chondroitin sulfate K (CS-K) from king crab cartilage rich in rare 3-O-sulfated glucuronic acid (GlcUA(3S)) displayed neuritogenic activity and affinity toward various growth factors like CS-E from squid cartilage. CS-K-mediated neuritogenesis of mouse hippocampal neurons in culture was abolished by...