Effect of doses on the bioavailability of phenytoin from a prompt-release and an extended-release preparation: Single dose study

• Main Authors: Rojanasthien N., Chaichana N., Teekachunhatean S., Kumsorn B., Sangdee C., Chankrachang S.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-35848931680&partnerID=40&md5=f93aaf38690252e89d479c66c16a9aa4; http://www.ncbi.nlm.nih.gov/pubmed/17957935; http://cmuir.cmu.ac.th/handle/6653943832/2148
• Institution: Chiang Mai University

Objective: To determine the effect of doses on the bioavailability of a prompt-release and an extended-release phenytoin capsule after given as single doses. Material and Method: Eight healthy male volunteers were given single oral doses of 100, 200, and 300 mg of a prompt-release preparation (Ditoi...