Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress

• Main Authors: Thephinlap C., Ounjaijean S., Khansuwan U., Fucharoen S., Porter J.B., Srichairatanakool S.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-34248657988&partnerID=40&md5=3804d23ae78ede3b952504c42a054b5d; http://www.ncbi.nlm.nih.gov/pubmed/17504202; http://cmuir.cmu.ac.th/handle/6653943832/2220
• Institution: Chiang Mai University

β-Thalassemia patients suffer from secondary iron overload caused by increased iron absorption and multiple blood transfusions. Excessive iron catalyzes free-radical formation, causing oxidative tissue damage. Non-transferrin bound iron (NTBI) detected in thalassemic plasma is highly toxic and chela...