Detection of β-thalassemia mutations using a multiplex amplification refractory mutation system assay

• المؤلفون الرئيسيون: Mirasena S., Shimbhu D., Sanguansermsri M., Sanguansermsri T.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-47949088545&partnerID=40&md5=4852ebc27b79005da2832a37eadf24cf; http://cmuir.cmu.ac.th/handle/6653943832/2402
• المؤسسة: Chiang Mai University

We developed two sets of a multiplex amplification refractory mutation system (M-ARMS) assay to identify specific β-thalassemia (β-thal) mutations that are common in Thailand. The first one was for the detection of mutants with codon 17 (A>T), IV S-I-1 (G >T)), codons 41/42 (-TCT T) and codons...