ATF6α induces XBP1-independent expansion of the endoplasmic reticulum

• Main Authors: Bommiasamy H., Back S.H., Fagone P., Lee K., Meshinchi S., Vink E., Sriburi R., Frank M., Jackowski S., Kaufman R.J., Brewer J.W.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-67650000500&partnerID=40&md5=57afd870088cb1c7853b5d7afd7dceb5; http://cmuir.cmu.ac.th/handle/6653943832/2859
• Institution: Chiang Mai University

A link exists between endoplasmic reticulum (ER) biogenesis and the unfolded protein response (UPR), a complex set of signaling mechanisms triggered by increased demands on the protein folding capacity of the ER. The UPR transcriptional activator X-box binding protein 1 (XBP1) regulates the expressi...