Identification of HLA-A24 restricted pre-erythrocytic stage specific T-cell epitopes using plasmodium falciparum synthetic peptides: a preliminary study

• Main Authors: Tippawangkosol P., Duangchanda T., Ubalee R., Ruengweerayut R., Hirayama K., Na-Bangchang K.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-59149092814&partnerID=40&md5=1860264f6200e222577372905d321127; http://www.ncbi.nlm.nih.gov/pubmed/19323028; http://cmuir.cmu.ac.th/handle/6653943832/2923
• Institution: Chiang Mai University

Fourteen (9 amino acids) peptides of Plasmodium falciparum pre-erythrocytic stage antigens, namely, TRAP, CTRP, LSA-1, STARP and MSP-1, restricted to HLA-A24 and specific to T-cell response were identified. The antigen-specific IFN-γ responses of these synthetic peptides in malaria exposed and non-m...