A dihydroxy-pentamethoxyflavone from Gardenia obtusifolia suppresses proliferation and promotes apoptosis of tumor cells through modulation of multiple cell signaling pathways
We sought to determine the molecular basis for the anticancer activities of 5,3′-dihydroxy-3,6,7,8,4′-penta-methoxyflavone (DH-PMF), isolated from Gardenia obtusifolia traditionally used in Thailand for a variety of ailments. As little as 1 μM DH-PMF inhibited the proliferation of prostate, colon, k...
محفوظ في:
المؤلفون الرئيسيون: | Phromnoi K., Reuter S., Sung B., Limtrakul P., Aggarwal B.B. |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
2014
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الوصول للمادة أونلاين: | http://www.scopus.com/inward/record.url?eid=2-s2.0-77958572996&partnerID=40&md5=180060881a1015f01946638563c16c99 http://cmuir.cmu.ac.th/handle/6653943832/3634 |
الوسوم: |
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مواد مشابهة
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A dihydroxy-pentamethoxyflavone from Gardenia obtusifolia suppresses proliferation and promotes apoptosis of tumor cells through modulation of multiple cell signaling pathways
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منشور في: (2018) -
A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents
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منشور في: (2014) -
Bioactive compounds from Gardenia obtusifolia Roxb. and Gardenia collinsae Craib
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منشور في: (2023) -
A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents
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منشور في: (2018) -
Cytotoxic and anti-HIV-1 constituents of Gardenia obtusifolia and their modified compounds
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منشور في: (2018)