Inhibition of P-glycoprotein activity and reversal of cancer multidrug resistance by Momordica charantia extract
Purpose: Multidrug resistance (MDR) is known as a problem limiting the success of therapy in patients treated long term with chemotherapeutic drugs. The drug resistance is mainly due to the overexpression of the 170 kDa P-glycoprotein (Pgp), which causes a reduction in drug accumulation in the cance...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-11144323815&partnerID=40&md5=f2f43c67b249924389c59322d5538d3b http://www.ncbi.nlm.nih.gov/pubmed/15248030 http://cmuir.cmu.ac.th/handle/6653943832/3702 |
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| Institution: | Chiang Mai University |
| Language: | English |