Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model

Background: The prevalence of drug resistance amongst the human malaria Plasmodium species has most commonly been associated with genomic mutation within the parasites. This phenomenon necessitates evolutionary predictive studies of possible resistance mutations, which may occur when a new drug is i...

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Main Authors: Tipsuwan W., Srichairatanakool S., Kamchonwongpaisan S., Yuthavong Y., Uthaipibull C.
格式: Article
語言:English
出版: 2014
在線閱讀:http://www.scopus.com/inward/record.url?eid=2-s2.0-79955732820&partnerID=40&md5=e212f440c5fad5dba0ed7e0319d597a9
http://cmuir.cmu.ac.th/handle/6653943832/3758
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機構: Chiang Mai University
語言: English