Resistance-associated mutations after initial antiretroviral treatment failure in a large cohort of patients infected with HIV-1 Subtype CRF01_AE

• المؤلفون الرئيسيون: Praparattanapan,J., Kotarathitithum,W., Chaiwarith,R., Nuntachit,N., Sirisanthana,T., Supparatpinyo,K.
• التنسيق: مقال
• منشور في: Bentham Science Publishers B.V. 2015
• الموضوعات: Infectious Diseases; Virology
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84872593049&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38249
• المؤسسة: Chiang Mai University

The nucleoside reverse transcriptase inhibitors (NRTIs), zidovudine (AZT) and stavudine (d4T) are thymidine analog drugs recommended as first-line antiretroviral therapy in HIV-1-naïve patients. Two thymidine analog mutation (TAM) pathways, TAM-1 and TAM-2, confer high levels of resistance with muta...