Improvement of the oligonucleotide ligation assay for detection of the M184V drug-resistant mutation in patients infected with human immunodeficiency virus type 1 subtype CRF01_AE

• Main Authors: Dokuta S., Utaipat U., Praparattanapan J., Keitkarn J., Maneekarn N., Sirisanthana T., Supparatpinyo K.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84876984572&partnerID=40&md5=8f4a8dd8e5497d1b95a2923858ee511c; http://www.ncbi.nlm.nih.gov/pubmed/23562659; http://cmuir.cmu.ac.th/handle/6653943832/4066
• Institution: Chiang Mai University

Methods based on genetic sequencing to monitor drug-resistance mutations in human immunodeficiency virus type 1 (HIV-1) require expensive instruments and are only capable of detecting mutant strains comprising >20% of virus populations. The National Institutes of Health's AIDS Research and R...