Resistance-Associated Mutations after Initial Antiretroviral Treatment Failure in a Large Cohort of Patients Infected with HIV-1 Subtype CRF01_AE

The nucleoside reverse transcriptase inhibitors (NRTIs), zidovudine (AZT) and stavudine (d4T) are thymidine analogue drugs recommended as first-line antiretroviral therapy in HIV-1-naïve patients. Two thymidine analogue mutation (TAM) pathways, TAM-1 and TAM-2, confer high levels of resistance with...

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Bibliographic Details
Main Authors: Praparattanapan J., Kotarathitithum W., Chaiwarith R., Nuntachit N., Sirisanthana T., Supparatpinyo K.
Format: Article
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/23061604
http://cmuir.cmu.ac.th/handle/6653943832/3992
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Institution: Chiang Mai University
Language: English