Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells

Aim: To compare the anti-cancer activity and cellular uptake of curcumin (Cur) delivered by targeted and non-targeted drug delivery systems in multidrug-resistant cervical cancer cells. Methods: Cur was entrapped into poly (DL-lactide-co-glycolide) (PLGA) nanoparticles (Cur-NPs) in the presence of m...

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Bibliographic Details
Main Authors: Punfa W., Yodkeeree S., Pitchakarn P., Ampasavate C., Limtrakul P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/22580738
http://www.scopus.com/inward/record.url?eid=2-s2.0-84862511071&partnerID=40&md5=0bff84b497b985ca38cef17fea418f33
http://cmuir.cmu.ac.th/handle/6653943832/3843
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Institution: Chiang Mai University
Language: English