Biological effects of curcumin-loaded PLGA nanoparticle conjugated with anti-p-glycoprotein antibody on multidrug resistant cancer cells in vitro and in animal models
Curcumin (Cur), a phenolic compound purified from the rhizome of Curcuma longa, has been reported to reduce both expression and function of P-glycoprotein (P-gp), a drug efflux pump. However, low level of oral bioavailability, poor absorption ability, a high metabolic rate, poor pharmacokinetics and...
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| 格式: | Theses and Dissertations |
| 語言: | English |
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เชียงใหม่ : บัณฑิตวิทยาลัย มหาวิทยาลัยเชียงใหม่
2020
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| 在線閱讀: | http://cmuir.cmu.ac.th/jspui/handle/6653943832/69409 |
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| 機構: | Chiang Mai University |
| 語言: | English |