Neolignans from leaves of Miliusa mollis
From the leaves of Miliusa mollis Pierre (Annonaceae), five new dihydrobenzofuran neolignans, namely miliumollin, 7-methoxymiliumollin, 3′-methoxymiliumollin, 4′-O-methylmiliumollin and miliumollinone, and a new 8-O-4′ neolignan named miliusamollin were isolated, and their structures were elucidated...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Elsevier
2015
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| Subjects: | |
| Online Access: | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84874671600&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38688 |
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| Institution: | Chiang Mai University |
| Summary: | From the leaves of Miliusa mollis Pierre (Annonaceae), five new dihydrobenzofuran neolignans, namely miliumollin, 7-methoxymiliumollin, 3′-methoxymiliumollin, 4′-O-methylmiliumollin and miliumollinone, and a new 8-O-4′ neolignan named miliusamollin were isolated, and their structures were elucidated through analysis of spectroscopic data. Miliumollin, 3′-methoxymiliumollin, miliumollinone and decurrenal exhibited weak cytotoxicity against KB, MCF7 and NCI-H187 cells. Miliumollinone possessed weak inhibitory effects against herpes simplex virus types 1 and 2. None of the isolates displayed inhibitory activity against avian influenza H5N1 neuraminidase. © 2013 Elsevier B.V. |
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