Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling

Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling

Responses to alpha interferon (IFN-α)-based treatment are dependent on both host and viral factors and vary markedly among patients infected with different hepatitis C virus (HCV) genotypes (GTs). Patients infected with GT3 viruses consistently respond better to IFN treatment than do patients infect...

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Main Authors: Kumthip K., Chusri P., Jilg N., Zhao L., Fusco D.N., Zhao H., Goto K., Cheng D., Schaefer E.A., Zhang L., Pantip C., Thongsawat S., O'Brien A., Peng L.F., Maneekarn N., Chung R.T., Lin W.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84865086668&partnerID=40&md5=9a98250d2f7e7c7f45bc0649c7a03495
http://www.ncbi.nlm.nih.gov/pubmed/22674974
http://cmuir.cmu.ac.th/handle/6653943832/3891
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Institution: Chiang Mai University
Language: English

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http://www.scopus.com/inward/record.url?eid=2-s2.0-84865086668&partnerID=40&md5=9a98250d2f7e7c7f45bc0649c7a03495
http://www.ncbi.nlm.nih.gov/pubmed/22674974
http://cmuir.cmu.ac.th/handle/6653943832/3891

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