Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling

Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling

Responses to alpha interferon (IFN-α)-based treatment are dependent on both host and viral factors and vary markedly among patients infected with different hepatitis C virus (HCV) genotypes (GTs). Patients infected with GT3 viruses consistently respond better to IFN treatment than do patients infect...

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Bibliographic Details
Main Authors: Kattareeya Kumthip, Pattranuch Chusri, Nikolaus Jilg, Lei Zhao, Dahlene N. Fusco, Hong Zhao, Kaku Goto, Du Cheng, Esperance A. Schaefer, Leiliang Zhang, Chansom Pantip, Satawat Thongsawat, Amornrat O'Brien, Lee F. Peng, Niwat Maneekarn, Raymond T. Chung, Wenyu Lin
Format: Journal
Published: 2018
Subjects:
Agricultural and Biological Sciences
Immunology and Microbiology
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84865086668&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51262
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Institution: Chiang Mai University

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http://cmuir.cmu.ac.th/jspui/handle/6653943832/51262

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