HLA class I serotypes and cytotoxic T-lymphocyte responses among human immunodeficiency virus-1-uninfected Thai volunteers immunized with ALVAC-HIV in combination with monomeric gp120 or oligomeric gp160 protein boosting

• Main Authors: Paris R., Bejrachandra S., Karnasuta C., Chandanayingyong D., Kunachiwa W., Leetrakool N., Prakalapakorn S., Thongcharoen P., Nittayaphan S., Pitisuttithum P., Suriyanon V., Gurunathan S., McNeil J.G., Brown A.E., Birx D.L., De Souza M.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-4344678172&partnerID=40&md5=e2836f8624aefba8575ca63ff41ac0b7; http://cmuir.cmu.ac.th/handle/6653943832/3892
• Institution: Chiang Mai University

Antigen-induced cellular immunogenicity may vary between populations due to differences in human leukocyte antigen (HLA) diversity and, hence, may play a critical role in the protection afforded by vaccines. In the setting of two, phase I/II human immunodeficiency virus-1 vaccine trials of a recombi...