A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost

A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost

BACKGROUND: The development of an effective HIV-1 vaccine is critical to control the pandemic. A prime-boost HIV-1 vaccine trial assessing safety and immunogenicity was conducted in Thailand as part of an evaluation of candidate regimens for a phase 3 efficacy trial. METHODS: ALVAC-HIV (vCP1521), ex...

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Main Authors: Prasert Thongcharoen, Vinai Suriyanon, Robert M. Paris, Chirasak Khamboonruang, Mark S. De Souza, Silvia Ratto-Kim, Chitraporn Karnasuta, Victoria R. Polonis, Lynn Baglyos, Raphaelle El Habib, Sanjay Gurunathan, Susan Barnett, Arthur E. Brown, Deborah L. Birx, John G. McNeil, Jerome H. Kim
Other Authors: Faculty of Medicine, Siriraj Hospital, Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24779
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/24779

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