Specific antibody responses to vaccination with bivalent CM235/SF2 gp120: Detection of homologous and heterologous neutralizing antibody to subtype E (CRF01.AE) HIV type 1

• Main Authors: Jerome H. Kim, Punnee Pitisuttithum, Chirasak Kamboonruang, Thippawan Chuenchitra, John Mascola, Sarah S. Frankel, Mark S. DeSouza, Victoria Polonis, Robert McLinden, Anna Sambor, Arthur E. Brown, Benjaluck Phonrat, Kittipong Rungruengthanakit, Anne Marie Duliege, Merlin L. Robb, John McNeil, Deborah L. Birx
• Other Authors: U.S. Military HIV Research Program
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20889
• Institution: Mahidol University

HIV-1 CRF.AE-01 (formerly subtype E) infection is highly prevalent in Southeast Asia. Despite success with public health measures, the development of an effective CRF01.AE vaccine is critical to the control of this epidemic. Sera from the open-label arms of the first clinical trial of a bivalent HIV...