Modulation of P-glycoprotein by Stemona alkaloids in human multidrug resistance leukemic cells and structural relationships

• المؤلفون الرئيسيون: Umsumarng S., Pitchakarn P., Yodkeeree S., Punfa W., Mapoung S., Ramli R., Pyne S., Limtrakul P.
• التنسيق: دورية
• منشور في: 2017
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85028725461&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40084

© 2017 Elsevier GmbH Background Multidrug resistance (MDR) is a major reason for the failure of chemotherapy in the treatment of cancer patients. P-gp over-expression in MDR cancer cells is a multifactorial phenomenon with biochemical resistance mechanisms. Stemofoline (STF), isolated from Stemona b...