Stemona alkaloids, from traditional Thai medicine, increase chemosensitivity via P-glycoprotein-mediated multidrug resistance
P-glycoprotein-mediated drug efflux can cause a multidrug resistance (MDR) phenotype that is associated with a poor response to cancer chemotherapy. Through bioassay-guided fractionation, active Stemona alkaloids were isolated from the roots of Stemona aphylla and S. burkillii. The chemical structur...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-78651336302&partnerID=40&md5=bb972698761568a8a72c9881acfb619e http://www.ncbi.nlm.nih.gov/pubmed/20739156 http://cmuir.cmu.ac.th/handle/6653943832/4527 |
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| Institution: | Chiang Mai University |
| Language: | English |