The antimicrobial peptide, human β-defensin-1, potentiates in vitro osteoclastogenesis via activation of the p44/42 mitogen-activated protein kinases

• Main Authors: Makeudom A., Supanchart C., Montreekachon P., Khongkhunthian S., Sastraruji T., Krisanaprakornkit J., Krisanaprakornkit S.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85024853295&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40125
• Institution: Chiang Mai University

© 2017 Elsevier Inc. Previous studies have demonstrated increased expression and raised levels of human β-defensin (hBD)-1 in gingival tissue and crevicular fluid of patients with chronic periodontitis and peri-implantitis, oral bone-resorbing diseases caused by enhanced osteoclastogenesis. Therefor...