Decline in CD4 T lymphocytes with monotherapy bridging strategy for non-adherent adolescents living with HIV infection: Results of the IMPAACT P1094 randomized trial

• Main Authors: Agwu A., Warshaw M., McFarland E., Siberry G., Melvin A., Wiznia A., Fairlie L., Boyd S., Harding P., Spiegel H., Abrams E., Carey V., Purswani M., Aurpibul L., Sirisanthana V., Khamrong C., Wilson J., Donnelly M., Swetnam J., Stankievich E., Ivalo S., Foradori I., Gomes I., Pilotto J., Da Silva C., Negra M., Lian Y., Pacola D., Anderson T., Noletto T.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85020697190&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/40446
• Institution: Chiang Mai University

Introduction: Management of persistently non-adherent youth living with HIV (YLHIV) with virologic failure (VF) on combination antiretroviral therapy (cART) remains challenging. One strategy has been using 3TC/FTC monotherapy (3TC/FTC), which in the presence of the M184V resistance mutation, does no...