Identification of Pfdhfr mutant variants in plasmodium berghei model

• Main Authors: Tipsuwan W., Srichairatanakool S., Kamchonwongpaisan S., Yuthavong Y., Uthaipibull C.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-84874528388&partnerID=40&md5=a527b25ef4cad2998dbb6d05ecd28453; http://cmuir.cmu.ac.th/handle/6653943832/4064

Parasite resistance to antimalarials is a major burden in controlling malaria disease. Genetic mutations within the parasites are found to be the factor in conferring resistance to drugs. In this study, the power of random mutant library and transgenic parasite systems were employed to identify muta...