Effects of vildagliptin vs. sitagliptin, on cardiac function, heart rate variability, and mitochondrial function in obese insulin resistant rats

BACKGROUND AND PURPOSE: Long-term high-fat diet (HFD) consumption has been shown to cause insulin resistance, which is characterized by hyperinsulinemia with metabolic inflexibility. Insulin resistance is associated with cardiac sympathovagal imbalance, cardiac dysfunction, and cardiac mitochondrial...

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Bibliographic Details
Main Authors: Apaijai N., Pintana H., Chattipakorn SC., Chattipakorn N.
Format: Article
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/23488656
http://cmuir.cmu.ac.th/handle/6653943832/4095
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Institution: Chiang Mai University
Language: English