Effects of vildagliptin vs. sitagliptin, on cardiac function, heart rate variability, and mitochondrial function in obese insulin resistant rats

• Main Authors: Apaijai N., Pintana H., Chattipakorn SC., Chattipakorn N.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.ncbi.nlm.nih.gov/pubmed/23488656; http://cmuir.cmu.ac.th/handle/6653943832/4095
• Institution: Chiang Mai University

BACKGROUND AND PURPOSE: Long-term high-fat diet (HFD) consumption has been shown to cause insulin resistance, which is characterized by hyperinsulinemia with metabolic inflexibility. Insulin resistance is associated with cardiac sympathovagal imbalance, cardiac dysfunction, and cardiac mitochondrial...