Toxicity of barakol: Hepatotoxicity and subacute toxicity

• Main Authors: Pumpaisalchai W., Kaewvichit S., Taesothikul T., Sanichwankul K., Siriaunkgul S., Niwatananun W.
• Other Authors: Brovelli EChansakaow S.Farias D.Hongratanaworakit T.Botero Omary M.Vejabhikul S.Craker L.E.Gardner Z.E.
• Format: Conference or Workshop Item
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84879908923&partnerID=40&md5=51d1faebf0af5b6895adf650e15e38ff; http://cmuir.cmu.ac.th/handle/6653943832/4121
• Institution: Chiang Mai University

Barakol, an active principle of Cassia siamea (Caesalpiniaceae), exhibits an anxiolytic property. This study was undertaken to evaluate the acute hepatotoxicity and subacute toxicity of barakol in rats. The LD50 of barakol after oral administration was 2.33 g/kg. In an acute hepatotoxicity study, si...