Toxicity of barakol: Hepatotoxicity and subacute toxicity

• المؤلفون الرئيسيون: Pumpaisalchai W., Kaewvichit S., Taesothikul T., Sanichwankul K., Siriaunkgul S., Niwatananun W.
• مؤلفون آخرون: Brovelli EChansakaow S.Farias D.Hongratanaworakit T.Botero Omary M.Vejabhikul S.Craker L.E.Gardner Z.E.
• التنسيق: Conference or Workshop Item
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-84879908923&partnerID=40&md5=51d1faebf0af5b6895adf650e15e38ff; http://cmuir.cmu.ac.th/handle/6653943832/4698

Barakol, an active principle of Cassia siamea (Caesalpiniaceae), exhibits an anxiolytic property. This study was undertaken to evaluate the acute hepatotoxicity and subacute toxicity of barakol in rats. The LD50 of barakol after oral administration was 2.33 g/kg. In an acute hepatotoxicity study, si...