Reactive center loop moiety is essential for the maspin activity on cellular invasion and ubiquitin-proteasome level

Maspin, a tumor suppressor (SERPINB5), inhibits cancer migration, invasion, and metastasis in vitro and in vivo. The tumor-suppressing effects of maspin depend in part on its ability to enhance cell adhesion to extracellular matrix. Although the molecular mechanism of maspin's action is still u...

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Bibliographic Details
Main Authors: Khanaree C., Chairatvit K., Roytrakul S., Wongnoppavich A.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84880309087&partnerID=40&md5=faaf729eb610f1e4b5ae8c6fb98e936c
http://www.ncbi.nlm.nih.gov/pubmed/23924927
http://cmuir.cmu.ac.th/handle/6653943832/4156
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Institution: Chiang Mai University
Language: English