Cisplatin-induced ototoxicity in pediatric solid tumors: The role of glutathione S-transferases and megalin genetic polymorphisms
Cisplatin-induced ototoxicity, an important dose-limiting side effect, has proven high interindividual variability. Glutathione S-transferases (GSTs) are isoenzymes involved in cellular detoxification processes. Megalin has been demonstrated to bind aminoglycosides, known to be similar to cisplatin...
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| Main Authors: | , , , , , , , |
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| 格式: | Article |
| 語言: | English |
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2014
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| 在線閱讀: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84878653311&partnerID=40&md5=b4a45002649869f05b7628112d98f30f http://cmuir.cmu.ac.th/handle/6653943832/4170 |
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| 機構: | Chiang Mai University |
| 語言: | English |