Potent vasorelaxant analogs from chemical modification and biotransformation of isosteviol
Isosteviol (1) has been reported to exhibit moderate vasorelaxant activity. In order to enhance the bioactivity of this compound, chemical modification of 1 to the dihydro analog, ent-16β-hydroxybeyeran-19-oic acid (2), was undertaken. Compound 2 was then converted to the corresponding acetate deriv...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84875987038&partnerID=40&md5=8e960fb167f1307eb2b959bc5a37adbc http://cmuir.cmu.ac.th/handle/6653943832/4174 |
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Institution: | Chiang Mai University |
Language: | English |