Potent vasorelaxant analogs from chemical modification and biotransformation of isosteviol

Isosteviol (1) has been reported to exhibit moderate vasorelaxant activity. In order to enhance the bioactivity of this compound, chemical modification of 1 to the dihydro analog, ent-16β-hydroxybeyeran-19-oic acid (2), was undertaken. Compound 2 was then converted to the corresponding acetate deriv...

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Bibliographic Details
Main Authors: Wonganan O., Tocharus C., Puedsing C., Homvisasevongsa S., Sukcharoen O., Suksamrarn A.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84875987038&partnerID=40&md5=8e960fb167f1307eb2b959bc5a37adbc
http://cmuir.cmu.ac.th/handle/6653943832/4174
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Institution: Chiang Mai University
Language: English
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