Synthesis of stemofoline analogues as acetylcholinesterase inhibitors

• Main Authors: Sastraruji K., Sastraruji T., Ung A., Griffith R., Jatisatienr A., Pyne S.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84863853821&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/42778
• Institution: Chiang Mai University

Thirty-two new stemofoline analogues were prepared from didehydrostemofoline for studies as AChE inhibitors. C-3 Side-chain modified amino, carbamate, triazole and oxazole stemofoline derivatives were prepared. In general the amine derivatives were found to be stronger inhibitors of AChE than their...