Biochemical Mechanism of Modulation of Human P-glycoprotein by Stemofoline

The resistance to chemotherapeutic drugs by cancer cells is considered to be one of the major obstacles for success in the treatment of cancer. A major mechanism underlying this multidrug resistance is the overexpression of P-glycoprotein (P-gp), resulting in insufficient drug delivery to the tumor...

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Bibliographic Details
Main Authors: Chanmahasathien W., Ohnuma S., Ambudkar S., Limtrakul P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-79960494077&partnerID=40&md5=ccfb611024bce76e823cda911be2c081
http://www.ncbi.nlm.nih.gov/pubmed/21786221
http://cmuir.cmu.ac.th/handle/6653943832/4555
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Institution: Chiang Mai University
Language: English