Biochemical mechanism of modulation of human p-glycoprotein by stemofoline

Biochemical mechanism of modulation of human p-glycoprotein by stemofoline

The resistance to chemotherapeutic drugs by cancer cells is considered to be one of the major obstacles for success in the treatment of cancer. A major mechanism underlying this multidrug resistance is the overexpression of P-glycoprotein (P-gp), resulting in insufficient drug delivery to the tumor...

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Bibliographic Details
Main Authors: Chanmahasathien,W., Ohnuma,S., Ambudkar,S.V., Limtrakul,P.N.
Format: Article
Published: Georg Thieme Verlag 2015
Subjects:
Analytical Chemistry
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Pharmacology
Organic Chemistry
Complementary and Alternative Medicine
Online Access:http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84155172846&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38520
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Institution: Chiang Mai University

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http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84155172846&origin=inward
http://cmuir.cmu.ac.th/handle/6653943832/38520

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