Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes

• Main Authors: Toegel S., Wu S.Q., Otero M., Goldring M.B., Leelapornpisid P., Chiari C., Kolb A., Unger F.M., Windhager R., Viernstein H.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-80051614317&partnerID=40&md5=726ea14fa8963ec46471f65464198741; http://cmuir.cmu.ac.th/handle/6653943832/4639
• Institution: Chiang Mai University

Exacerbated production of matrix metalloproteinases (MMPs) is a key event in the progression of osteoarthritis (OA) and represents a promising target for the management of OA with nutraceuticals. In this study, we sought to determine the MMP-inhibitory activity of an ethanolic Caesalpinia sappan ext...