Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla

Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited an...

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Main Authors: Sarot Cheenpracha, Thunwadee Ritthiwigrom, Surat Laphookhieo
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/47997
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-479972018-04-25T08:46:30Z Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla Sarot Cheenpracha Thunwadee Ritthiwigrom Surat Laphookhieo Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC 50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy. 2018-04-25T08:46:30Z 2018-04-25T08:46:30Z 2013-04-26 Journal 15206025 01633864 2-s2.0-84876930059 10.1021/np3006937 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/47997
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC 50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy.
format Journal
author Sarot Cheenpracha
Thunwadee Ritthiwigrom
Surat Laphookhieo
spellingShingle Sarot Cheenpracha
Thunwadee Ritthiwigrom
Surat Laphookhieo
Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
author_facet Sarot Cheenpracha
Thunwadee Ritthiwigrom
Surat Laphookhieo
author_sort Sarot Cheenpracha
title Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_short Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_full Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_fullStr Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_full_unstemmed Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_sort alstoniaphyllines a-c, unusual nitrogenous derivatives from the bark of alstonia macrophylla
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876930059&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/47997
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