Inhibition of P-glycoprotein mediated multidrug resistance by stemofoline derivatives

• Main Authors: Sonthaya Umsumarng, Komsak Pintha, Pornsiri Pitchakarn, Kwankamol Sastraruji, Thanapat Sastraruji, Alison T. Ung, Araya Jatisatienr, Stephen G. Pyne, Pornngarm Limtrakul
• Format: Journal
• Published: 2018
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876493908&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/48037
• Institution: Chiang Mai University

Resistance to chemotherapy in cancer patients has been correlated to the overexpression of the ATPbinding cassette (ABC) drug transporters including P-glycoprotein (P-gp) that actively efflux chemotherapeutic drugs from cancer cells. We examined the mutidrug resistance reversing property of stemofol...