Potent vasorelaxant analogs from chemical modification and biotransformation of isosteviol

Isosteviol (1) has been reported to exhibit moderate vasorelaxant activity. In order to enhance the bioactivity of this compound, chemical modification of 1 to the dihydro analog, ent-16β-hydroxybeyeran-19-oic acid (2), was undertaken. Compound 2 was then converted to the corresponding acetate deriv...

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Bibliographic Details
Main Authors: Orawan Wonganan, Chainarong Tocharus, Chonticha Puedsing, Sureeporn Homvisasevongsa, Oratai Sukcharoen, Apichart Suksamrarn
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875987038&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/48038
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Institution: Chiang Mai University

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