Potent vasorelaxant analogs from chemical modification and biotransformation of isosteviol
Isosteviol (1) has been reported to exhibit moderate vasorelaxant activity. In order to enhance the bioactivity of this compound, chemical modification of 1 to the dihydro analog, ent-16β-hydroxybeyeran-19-oic acid (2), was undertaken. Compound 2 was then converted to the corresponding acetate deriv...
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Main Authors: | Orawan Wonganan, Chainarong Tocharus, Chonticha Puedsing, Sureeporn Homvisasevongsa, Oratai Sukcharoen, Apichart Suksamrarn |
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Format: | Journal |
Published: |
2018
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Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875987038&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/48038 |
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Institution: | Chiang Mai University |
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