Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells
Cancer cells evade replicative senescence by re-expressing telomerase, which maintains telomere length and hence chromosomal integrity. Telomerase inhibition would lead cancer cells to senesce and therefore prevent cancer cells from growing indefinitely. G-quadruplex ligands can attenuate telomerase...
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| Main Authors: | , , , , , |
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| 格式: | 雜誌 |
| 出版: |
2018
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| 在線閱讀: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84873312526&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/48107 |
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| 機構: | Chiang Mai University |