Litchi chinensis-derived terpenoid as anti-HIV-1 protease agent: Structural design from molecular dynamics simulations

• Main Authors: Piyarat Nimmanpipug, Vannajan S. Lee, Peter Wolschann, Supot Hannongbua
• Format: Journal
• Published: 2018
• Subjects: Chemical Engineering; Chemistry; Computer Science; Materials Science; Mathematics; Physics and Astronomy
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70449589336&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/48942
• Institution: Chiang Mai University

The molecular structures of the binding between human immunodeficiency virus-1 protease (HIV-1PR) and various inhibitors including existing extensive natural products extracts have been investigated for anti-HIV drug development. In this study, the binding of HIV-1PR and a terpenoid from Litchi chin...