Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1

Because constitutive activation of signal transducers and activators of transcription-3 (STAT3) has been linked with cellular transformation, survival, proliferation, chemoresistance, and angiogenesis of various tumor cells, agents that can suppress STAT3 activation have potential as cancer therapeu...

Full description

Saved in:
Bibliographic Details
Main Authors: Kanokkarn Phromnoi, Sahdeo Prasad, Subash Gupta, Ramaswamy Kannappan, Simone Reuter, Pornngarm Limtrakul, Bharat B. Aggarwal
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80054782411&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49674
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University

Internet

https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80054782411&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49674

Similar Items