Genome screening for reducing type I polyketide synthase genes in tropical fungi associated with medicinal plants

• Main Authors: Juangjun Jumpathong, Yasuyo Seshime, Isao Fujii, John Peberdy, Saisamorn Lumyong
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80051547077&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49686
• Institution: Chiang Mai University

The aim of this work was to employ primers, which encode ketosynthase (KS) domains designed to detect Lovastatin-type PKSs (highly reduced molecules), to identify fungal species that have the potential for polyketide production. Using this strategy we have identified twenty-three KS sequences from t...