Synthesis of (R)-Mellein by a partially reducing iterative polyketide synthase

Mellein and the related 3,4-dihydroisocoumarins are a family of natural products with interesting biological properties. The mechanisms of dihydroisocoumarin biosynthesis remain largely speculative today. Here we report the synthesis of mellein by a partially reducing iterative polyketide synthase (...

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Main Authors: Sun, Huihua, Ho, Chun Loong, Ding, Feiqing, Soehano, Ishin, Liu, Xue-Wei, Liang, Zhao-Xun
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2013
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在線閱讀:https://hdl.handle.net/10356/97615
http://hdl.handle.net/10220/11204
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機構: Nanyang Technological University
語言: English