Insights into the programmed ketoreduction of partially reducing polyketide synthases : stereo- and substrate-specificity of the ketoreductase domain

Insights into the programmed ketoreduction of partially reducing polyketide synthases : stereo- and substrate-specificity of the ketoreductase domain

One of the hallmarks of iterative polyketide synthases (PKSs) is the programming mechanism which is essential for the generation of structurally diverse polyketide products. In partially reducing iterative PKSs (PR-PKSs), the programming mechanism is mainly dictated by the ketoreductase (KR) domain....

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Bibliographic Details
Main Authors: Soehano, Ishin, Yang, Lifeng, Ding, Feiqing, Sun, Huihua, Low, Zhen Jie, Liu, Xuewei, Liang, Zhao-Xun
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Subjects:
DRNTU::Science::Biological sciences::Molecular biology
Online Access:https://hdl.handle.net/10356/106999
http://hdl.handle.net/10220/25227
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/106999
http://hdl.handle.net/10220/25227

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