Prediction of the disulphide bonding state of cysteines in proteins using Conditional Random Fields

• المؤلفون الرئيسيون: Watshara Shoombuatong, Patrinee Traisathit, Sukon Prasitwattanaseree, Chatchai Tayapiwatana, Robert Cutler, Jeerayut Chaijaruwanich
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Computer Science; Social Sciences
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79960970337&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49705
• المؤسسة: Chiang Mai University

The formation of disulphide bonds between cysteines plays a major role in protein folding, structure, function and evolution. Many computational approaches have been used to predict the disulphide bonding state of cysteines. In our work, we developed a novel method based on Conditional Random Fields...